Current pre-exposure prophylaxis (PrEP) information
The NCCC provides clinical guidance and resources on PrEP (pre-exposure prophylaxis), the daily use of oral antiretroviral drugs by a non HIV-infected person as part of an HIV prevention regimen. The NCCC’s advice on the indications for and implementation of PrEP is based on guidelines and current medical literature and best practices. We have collected resources below to aid you in PrEP decision-making and in providing PrEP management assistance to your patients.
Up-to-date guidelines for PrEP management
Current U.S. Public Health Service guidelines and treatment protocols for managing PrEP. Guidelines on this page are revised as USPHS guidelines are updated.
PrEP Guidelines
2021 PrEP Guidelines from the Centers for Disease Control and Prevention (CDC):
- Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update
Open PDF | From the Centers for Disease Control and Prevention (CDC)
- Clinical Providers’ Supplement: Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update
Open PDF | From the Centers for Disease Control and Prevention (CDC)
Guidance from Previous Years
If you are interested in reading previous years’ CDC guidelines and recommendations pertaining to PrEP and the prevention of new HIV infections, please refer to their online archives.
PrEP resources for clinicians including patient education materials
We’ve compiled recommendations, tools, and literature to aid you in providing the highest-quality PrEP management services in your practice.
PrEP Resources
- CDC PrEP Guidances for Clinicians, Prevention Providers, and At-Risk Persons
Open Link | From CDC.gov
- CDC PrEP Providers’ Fact Sheet
Open PDF | From CDC.gov
- HIV.gov PrEP Information
Open Link | From HIV.gov
- New York State Department of Health Clinical Education Initiative PrEP Resources
Open Link | From NYSDOH/AIDS Institute
- New York State Department of Health/AIDS Institute PrEP FAQ Resource for Patients
Open Link | From NYSDOH/AIDS Institute
University of California, San Francisco |