Infant Care

Infant Care
Care of infants exposed to HIV is of paramount importance in successfully preventing perinatal transmission. HIV-exposed infants take HIV medication as prophylaxis and require special follow-up for the first few months of life until they are confirmed to have no detectable HIV. NCCC can assist you in providing this care.

Advice on treating HIV-exposed newborns

Perinatal HIV specialists are available 24/7 to answer calls about managing the care of infants exposed to HIV. Our clinicians have access to the most up-to-date information and literature for care, an experienced HIV community of practice at UCSF/SFGH, and a network of practitioners across the country who provide co-management and other resources.

Guidance on managing pediatric PEP

The CDC released updated non-occupational PEP guidelines in September 2025. Regimen selection and dosing information for non-perinatally exposed infants, children, and adolescents (e.g. found needles) can be found in Tables 4, 5, and 6 on pages 32-43 of the guidelines. Per guideline recommendations, clinicians should call NCCC at 844-ASK-NCCC (275-6222) for assistance with all known or possible exposures.

Note: The resources on this page are kept for archival purposes; please refer to the latest information on our Perinatal Guidelines and PEP Guidelines pages.

Infant Care Resources

  • The High-Risk HIV-Exposed Newborn: Obstetric and Infant Care Implications | NCCC CROI 2014 discussion
    Open PDF Open PDF | From the National Clinician Consultation Center
  • Informed Choice Breastfeeding in a Resource-Rich Setting | NCCC CROI 2012 discussion
    Open PDF Open PDF | From the National Clinician Consultation Center
  • Informed Choice Breastfeeding in a Resource-Rich Setting | NCCC CROI 2012 discussion slides
    Open PDF Open PDF | From the National Clinician Consultation Center

Helpful Links

  • Antiretroviral Management of Newborns with Perinatal HIV Exposure or HIV Infection
    Visit website | From clinicalinfo.hiv.gov