PrEP Resources

Current pre-exposure prophylaxis (PrEP) information

The NCCC provides clinical guidance and resources on PrEP (pre-exposure prophylaxis), which involves the use of antiretroviral medicines to prevent HIV acquisition before potential exposures. The NCCC’s advice on the indications for and implementation of PrEP is based on guidelines and current medical literature and best practices. We have collected resources below to aid you in PrEP decision-making and in providing PrEP management assistance to your patients.

PrEP Guidelines

Latest Guidelines for PrEP Management

Current U.S. Public Health Service guidelines and treatment protocols for managing PrEP. Guidelines on this page are revised as USPHS guidelines are updated.

» See All PrEP Guidelines


PEP Quick Guide

PrEP Quick Guide

This NCCC pre-exposure prophylaxis (PrEP) Quick Guide aims to provide a basic framework for clinicians and was developed based on commonly asked questions received on the NCCC’s PrEPline.

» Link to PrEP Quick Guide page

PrEP Tools for Clinicians

PrEP Tools for Clinicians, including patient education materials

We’ve compiled recommendations, tools, and literature to aid you in providing the highest-quality PrEP management services in your practice.

» Link to PrEP Tools for Clinicians page